Egg Donation Hospital in Ahmedabad

Donation

Egg Donation

An egg donor woman donates her eggs to an infertile couple, which are fertilized with the husband’s sperm, and resulting good grade embryos are transferred back to the wife’s uterus after optimal preparation. Donor eggs offer women with ovarian failure or no ovaries the possibility of having children. This is a great way to help a couple achieve their dream of becoming parents. Patients often resort to donor eggs as a last resort. It is crucial to fully understand the process before making a decision. Donor eggs will produce a healthy baby, and it is far cheaper than repeated unsuccessful attempts. Patients often have many questions and concerns when discussing donor egg procedures. Donor eggs are more likely to result in a pregnancy than any other treatment. This would allow more families to experience the joy of welcoming a baby into their lives. MAA Women's Hospital seeks to provide egg donation services with the consent and protection of the couple.

Indication

Advanced age of female partner(>40 years) is associated with a decline in quantity and quality of her eggs and hence decreased fertility.
Certain women suffer from decreased ovarian reserve( low AMH) even before they reach 40 years of age
Early onset of menopause (premature ovarian failure) which can occur in women as early as their 20’s or 30’s can require a woman to use donor eggs to grow her family.
Some women are born without ovaries or other reproductive organs. Sometimes a woman’s reproductive organs have been damaged due to disease or have been forced to have them surgically removed or those whose ovaries have been damaged by chemotherapy or radiotherapy which she may have undergone for cancer treatment.
Another indication would be a genetic disorder on part of the woman that can be over-comed by using eggs from healthy egg donor.
Many women have none of these issues, but continue to be unsuccessful using their own eggs (multiple IVF failure)

Congenital absence of eggs

Turner syndrome
Gonadal dysgenesis

Other

Diseases of X-chromosome linkage
Repetitive fertilization or pregnancy failure
Ovaries inaccessible for egg retrieval

Acquired reduced egg quantity / quality

Oophorectomy
Premature menopause
Chemotherapy
Radiation therapy
Autoimmunity – (for eg. Hypothyroidism, diabetes mellitus)
Advanced maternal age

Donor screening

First, it will be necessary for the donor to undergo a thorough medical examination, including a pelvic exam, blood draw to check health status and to test for infectious diseases, and an ultrasound to examine her ovaries, uterus and other pelvic organs.

Our screening criteria

Donor age – 21 -30 years
Ever married
Has borne atleast one healthy child of her own
Healthy
Family history – does not have any inheritable disease
Blood tests – Blood Group, Complete blood count, random blood sugar, serum creatinine (renal function tests), SGPT (liver function tests), PT – INR ( Blood co-agulation test), Urine routine microscopy, HIV, Hepatitis B, Hemoglobin electrophoeresis (Thalassemia screening), TSH (THYROID FUNCTION TEST)
These evaluations are necessary to ensure that the donor is fully prepared and capable of completing the donation cycle safely and successfully.

Legally anonymous

In India egg donations are legally anonymous as per ICMR guidelines, which means that neither egg donor nor infertile couple to whom she donates her eggs are known to each other. Neither is aware of other’s identity.

Donor matching & egg donor profiles

After donor is screened and deemed eligible for egg donatio
Matching involves allocating same blood group egg donor to the recipient
Recipient is allotted donor of similar physical characteristics – height, weight, complexion, hair colour, eye colour.
Recipients are provided with the matching donor’s profiles, among which they may select their preferred donor. Donor profile is provided in the following format : M1 form as per ICMR guidelines

Egg donation procedure

Once the screening is complete, consent is signed by her and her husband to withdraw all legal rights to the offspring that shall be born thus.
After selection of a matching egg donor for a recipient their menstrual cycles are synchronized with help of birth control pills.
Donor is administered injections from day 2/3 of her menstrual cycle for a period of 8-10 days on antagonist ( short) protocol , during this time she undergoes trans vaginal sonography to detect follicular size and number on 2-3 occasions, egg retrieval is planned once follicles are mature sized.
On day of donor’s egg retrieval, recipient couple’s husband is asked to give an ejaculated semen sample. When husband of recipient couple cannot produce a semen sample on the same day or is unavailable on that day, then his previously frozen semen sample can be used to fertilise the donor eggs.
Eggs thus collected are fertilized with recipient couple’s husband’s sperm and resulting good grade embryos are transferred back to uterus of recipient couple’s wife and excess are frozen for future use if necessary for the recipient couple only.

Embryo Donation

A couple who requires both donor egg and donor sperm due to reasons enlisted below are transferred with embryos formed from donor gametes in the IVF laboratory.

Indications

The infertile couple, husband sperm cannot be retrieved even after surgical techniques and wife requires egg donation due to indications mentioned in previous section.
Can’t afford or can’t pursue adoption
Can’t afford more expensive fertility treatments like ICSI with surgically retrieved sperm
Have been unsuccessful with other forms of ART
Are at high risk of passing down genetic disorders but cannot pursue PGD.

Why Pursue Embryo Donation?

There are a number of benefits to turning to embryo donation in order to conceive:
Embryo donation is usually less expensive than other ART procedures, like ICSI with surgical sperm retrieval.
It is less complicated and expensive than adoption.
Embryo donation can help you to become pregnant and give birth within one year.

Drawbacks to Embryo Donation

Child born through embryo donation is not genetically related to the intended parents.

How Do You Go About Embryo Donation IVF?

Embryo donation is typically offered by fertility clinics specializing in the field.
Contrary to popular belief, only donor’s gametes can be used to form embryos for embryo donation, embryo donation can never be performed with infertile couples excess remaining embryos as per ICMR guidelines.

Procedure for embryo donation

After donor matching is done and donors screened and deemed eligible, recipient and egg donor’s menstrual cycle are synchronized with contraceptive pills if necessary.
The recipient’s endometrium is prepared wither through hormone replacement therapy or it can be done in recipients natural cycle or modified natural cycle and embryos are transferred at optimal time.

Sperm donor matching

We obtain donor sperm from a sperm bank, which has been sufficiently tested to prove sperm donors healthy condition at time of sperm donation after matching with husband’s blood group, physical characteristics( height, weight, complexion, eye colour, hair colour), educational qualifications, occupation.

Is Embryo Donation Safe?

Embryo donation is an extremely safe procedure, with all donors undergoing proper diagnostic screening prior to donation.
Many patients wonder if obtaining an embryo from donors could harm them in any way as it does not contain any of their genetic material, however there have been several successful pregnancies after the first child born thus in , and a donor embryo does not illicit any graft versus host reaction in the female.